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Pedialyte AdvancedCare Plus vs Powerade Zero at CVS: Which Electrolyte Is Better?

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SLF Electrolyte Comparison · 2026

Pedialyte AdvancedCare Plus

Pedialyte AdvancedCare Plus

★★★★☆4.2/5

Exercise & Workouts · Kids And Adults Replacing Significant Fluid And Electrolyte Losses From Vomiting · Diarrhea

Check Price at CVSRead full review ↗
VS
Powerade Zero

Powerade Zero

★★★★☆4.2/5

Hot-Weather Endurance · Everyday Hydration · Exercise & Workouts

Check Price at CVSRead full review ↗
🏆 Overall Winner

Powerade Zero

Best overall data score for this matchup based on formula, value, rating, and intended use.

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Explore Both Brands

Continue to the full Brand Hubs for products, flavors, buying guides, and every published comparison.

🏆Overall WinnerPowerade Zero
💧Highest SodiumPedialyte AdvancedCare Plus
◆Lowest SugarPedialyte AdvancedCare Plus
🏷Best ValuePowerade Zero
🏃Best for EndurancePedialyte AdvancedCare Plus
★Top RatedTie
▤

At a Glance

A quick side-by-side look at nutrition, value, and overall performance.

FeaturePedialyte AdvancedCare PlusPowerade Zero🏆 Edge
💧Sodium490 mg400 mgPedialyte AdvancedCare Plus
🌿Potassium280 mg130 mgPedialyte AdvancedCare Plus
MgMagnesiumNot listedNot listedTie
◆Sugar7.0 g0.0 gPedialyte AdvancedCare Plus
🔥Calories350Pedialyte AdvancedCare Plus
🍃SweetenerDextrose, sucralose, acesulfame potassiumSucralose and Acesulfame PotassiumPreference
🏷Cost per serving$2.66$1.99Powerade Zero
★SLF rating★★★★☆4.2/5★★★★☆4.2/5Tie
🌿

Functional Ingredients

Additional active or performance-oriented ingredients recorded in the SLF database.

Pedialyte AdvancedCare Plus

  • PreActiv prebiotics (galactooligosaccharides)
  • zinc

A top choice for high-electrolyte oral rehydration when illness, heat or prolonged exercise causes substantial fluid loss, but more electrolyte-heavy than necessary for routine…

Powerade Zero

  • Vitamin C
  • Vitamin B12

Best as a convenient budget sports drink, not as a premium or clean-label electrolyte.

Key Differences

The most meaningful data-backed differences in this matchup.

Higher SodiumModerate difference

Pedialyte AdvancedCare Plus

490 mg+90 mg400 mg

Why it matters: Higher sodium can better replace larger sweat losses during prolonged exercise or heat.

Lower SugarMajor difference

Powerade Zero

7.0 g−7.0 g0.0 g

Why it matters: Lower sugar may suit people prioritizing reduced-sugar hydration.

Better ValueModerate difference

Powerade Zero

$2.66−$0.67$1.99

Why it matters: A lower cost per serving can make frequent use more practical.

More PotassiumMajor difference

Pedialyte AdvancedCare Plus

280 mg+150 mg130 mg

Why it matters: Potassium supports fluid balance and normal muscle function.

◉

Who Should Choose Each Product?

Use these guidelines to find the best fit for your hydration needs and lifestyle.

Choose Pedialyte AdvancedCare Plus if…

  • Exercise & Workouts
  • Kids And Adults Replacing Significant Fluid And Electrolyte Losses From Vomiting
  • Diarrhea
  • Extreme Heat Or Prolonged Exercise

A top choice for high-electrolyte oral rehydration when illness, heat or prolonged exercise causes substantial fluid loss, but more electrolyte-heavy than necessary for routine hydration.

Choose Powerade Zero if…

  • Hot-Weather Endurance
  • Everyday Hydration
  • Exercise & Workouts
  • Travel
  • Heat & Outdoor Work
  • Keto & Low-Carb
  • Budget Hydration
  • Gym Workouts

Best as a convenient budget sports drink, not as a premium or clean-label electrolyte.

Pros and Considerations

Pedialyte AdvancedCare Plus

✓ Strengths

  • Moderate sodium level suits everyday hydration needs
  • Provides meaningful potassium

● Keep in Mind

  • Contains 7.0 g sugar per serving
  • Magnesium amount is not disclosed in the current SLF record
  • Premium cost per serving

Powerade Zero

✓ Strengths

  • Moderate sodium level suits everyday hydration needs
  • Sugar-free formula
  • Fits keto and low-carbohydrate lifestyles

● Keep in Mind

  • Magnesium amount is not disclosed in the current SLF record
  • Premium cost per serving
🎯 SLF Recommendation
Overall Winner

Powerade Zero

SLF scoring considers nutrition, formula, price, certifications, intended use, and value.

Why it earns the edge

  • Moderate sodium level suits everyday hydration needs
  • Sugar-free formula
  • Fits keto and low-carbohydrate lifestyles

Choose Pedialyte AdvancedCare Plus instead if you:

  • Exercise & Workouts
  • Kids And Adults Replacing Significant Fluid And Electrolyte Losses From Vomiting
  • Diarrhea
  • Extreme Heat Or Prolonged Exercise
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Frequently Asked Questions

Data-backed answers based on the current SLF product records.

Which has more sodium?

Pedialyte AdvancedCare Plus contains 490 mg of sodium per serving, compared with 400 mg. Higher sodium may be more useful when replacing larger sweat losses during prolonged exercise or hot conditions.

Which has less sugar?

Pedialyte AdvancedCare Plus has less sugar at 7.0 g per serving, versus 0.0 g. This may matter for people limiting added sugar.

Which is less expensive per serving?

Powerade Zero is currently less expensive at $1.99 per serving, compared with $2.66. Pricing can change by retailer and package size.

What functional ingredients does each product include?

Pedialyte AdvancedCare Plus lists PreActiv prebiotics (galactooligosaccharides), zinc. Powerade Zero lists Vitamin C, Vitamin B12. Functional ingredients supplement the core electrolyte profile but do not automatically make one product better for every use.

Which product is better overall?

Powerade Zero earns the higher SLF comparison score based on the available formula, value, rating, and intended-use data. Pedialyte AdvancedCare Plus may still be the better fit when its specific use cases align more closely with your needs.

Nutrition facts, pricing, and availability can change. Verify the current label before purchasing. This comparison is informational and is not medical advice.

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